nals was approximated by a network of vertices forming isosceles triangles with average basis (perpendicular to the bone surface) of 251 В± 13 micrometers and height (parallel to the bone surface) of 258 В± 24 micrometers.
Osteocyte lacunar density in individual bone areas underlying the lateral, medial and posterior surfaces of tibial shaft. ( mean В± SD of 7 disectors) [mm-3]
layer:
facies lateralis
facies medialis
facies posterior
cortical
18958 В± 2409
19119 В± 3488
22991 В± 4017
medulllar
17218 В± 1566
14191 В± 2122
17453 В± 1603
Discussion
- biological interpretation of quantitative parameters
- ДЌasovГЎ naroДЌnost
- disektor-obecne v MM jedinnГЎ metoda umoЕѕnujici 3D
- srovnГЎnГ/pЕ™epoДЌet 2D a 3D, vzorec
- Conclusion
We suggest the combination of optical disector, stereological point-counting method, and Delaunay triangulation to be a set of complementary methods useful for description of local heterogeneities in lacunar density and arrangement of vascular canals in microstructure of compact bone.
References:
[1] RAUCH F, Watching bone cells at work: what we can see from bone biopsies, Pediatr Nephrol, 21: 457-462, 2006
[2] RAUCH F (2003) Bone histomorphometry. In: Glorieux FH, Pettifor J, Jueppner H (eds) Pediatric bone. Academic, San Diego, CA, pp 359-374
[3] RAUCH F, Travers R, Norman ME, Taylor A, Parfitt AM, Glorieux FH (2002) The bone formation defect in idiopathic juvenile osteoporosis is surface-specific. Bone 31:85-89
[3] GLORIEUX FH, Travers R, Taylor A, Bowen JR, Rauch F, Norman M, Parfitt AM (2000) Normative data for iliac bone histomorphometry in growing children. Bone 26:103-109
[4] PARFITT AM, Drezner MK, Glorieux FH, Kanis JA, Malluche H, Meunier PJ, Ott SM, Recker RR (1987) Bone histomorphometry: standardization of nomenclature, symbols, and units.Report of the ASBMR Histomorphometry Nomenclature Committee. J Bone Miner Res 2:595-610
Acknowledgments: Supported by the project MSM0021620819 and by the grant GAAV 100110502.
